Improved performance of intensive semicontinuous cultures of Scenedesmus by biomass recirculation

Engineering Escherichia coli to improve

Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions

✍ Alvaro R. Lara; Consuelo Vazquez-Limón; Guillermo Gosset; Francisco Bolívar; Agu 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB 👁 2 views

## Abstract Three __E. coli__ strains, named VAL22, VAL23, and VAL24, were engineered at the level of mixed‐acid fermentation pathways to improve culture performance under transient anaerobic conditions. VAL22 is a single mutant with an inactivated __poxB__ gene that codes for pyruvate oxidase whic