Improved method of an unusual conversion of aliphatic amines into alcohols

✍ Scribed by S.M.Abdur Rahman; Hiroaki Ohno; Tetsuaki Tanaka

• Book ID: 104231728
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 62 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01680-x

✦ Synopsis

An improved method for the synthesis of alcohols from amines was achieved using a degassed diethylene glycol and KOH. Utilizing this method, facile conversion of a cyano group, even a sterically hindered one, to a hydroxy-methyl group was also accomplished.