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IMPROVED HORNER-WADSWORTH-EMMONS PREPARATION OF α-METHYL- OR α-ETHYL-α,β-UNSATURATED ESTERS FROM ALDEHYDES

✍ Scribed by Petroski, Richard J.; Weisleder, David


Book ID
126629335
Publisher
Taylor and Francis Group
Year
2001
Tongue
English
Weight
124 KB
Volume
31
Category
Article
ISSN
0039-7911

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✍ Shigeki Sano; Kenji Yokoyama; Rie Teranishi; Motoo Shiro; Yoshimitsu Nagao 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 106 KB

The enantioselective Horner-Wadsworth-Emmons reaction of 2-fluoro-2-diethylphosphonoacetates with s-symmetric prochiral 2-substituted-1,3-dioxan-5-ones and 4-substituted-cyclohexanones was investigated by employing Sn(OSO 2 CF 3 ) 2 and N-ethylpiperidine in the presence of an external chiral ligand,