Improved glycemia by hepatic insulin gene expression in insulin-dependent diabetes mellitus
β Scribed by Nuria Morral; Hengjiang Dong; Robert MvEvoy; Marcia Meseck; SavioL.C. Woo
- Book ID
- 117369578
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 114 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0168-8227
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The insulin receptor has been proposed as a candidate gene for the inherited defect in Type 2 (non-insulin-dependent) diabetes mellitus and we therefore studied three restriction fragment length polymorphic sites, two revealed with the enzyme Sst1 and one by Rsa1, using two insulin receptor cDNA pro
The effect of glucagon infusion on hepatic glucose production during euglycaemia was evaluated in seven Type i (insulin-dependent) diabetic patients and in ten control subjects. In the diabetic subjects normoglycaemia was maintained during the night preceding the study by a variable intravenous insu