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Improved extraction of penicillin G using hydrocarbon sulfoxides

โœ Scribed by Wen Lei; Zhou Li

Publisher
Wiley (John Wiley & Sons)
Year
2004
Tongue
English
Weight
105 KB
Volume
79
Category
Article
ISSN
0268-2575

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โœฆ Synopsis

Abstract

Extraction of penicillin G with sulfoxide extractants, petroleum sulfoxide (PSO) and diโ€isooctyl sulfoxide (DISO) was researched systematically. Based on research of the extraction equilibrium of penicillin G, the suitable extraction and reโ€extraction conditions were determined, and then extraction cascade and benchโ€scale experiments were carried out. The performance of extraction systems composed of PSO and DISO, with sulfonated kerosene as the diluent, is superior to that of nโ€butyl acetate owing to the low solubility of these new extractants in water. Their consumption during the extraction process was lower, and the recovery step of extractants from aqueous raffinate was eliminated. Copyright ยฉ 2004 Society of Chemical Industry

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