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Improved enantioselective synthesis of anti α-methyl-β-hydroxyesters through TiCl4-PPh3 mediated aldol condensation

✍ Scribed by Camillo Palazzi; Lino Colombo; Cesare Gennari


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
201 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis


The complex between TiCl and PPh addition of silyl ketenelacetals 2 effectively catalyses the aldol o aldehydes dramatically improving the anti-syn ratios.