Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion
โ Scribed by Chen, Liyuan; Dang, Qifeng; Liu, Chengsheng; Chen, Jun; Song, Lei; Chen, Xiguang
- Book ID
- 113087846
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- English
- Weight
- 398 KB
- Volume
- 6
- Category
- Article
- ISSN
- 2095-0217
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Several formulation approaches were attempted to improve the dissolution and the oral absorption of ER-34122, which is a novel dual 5-lipoxygenase/ cyclooxygenase inhibitor with potent anti-inยฏammatory activity. The solid dispersion of ER-34122 with hydroxypropylmethylcellulose (TC-5RW), which is an
## Abstract Embolization of blood vessels may result in a variety of side effects which can include pain and inflammation. The objective of this study was to assess the release and effect of ibuprofen (IBU) from Bead Blockโข microspheres (BB) loaded with IBU (IBUโBB) on the foreign body inflammatory