Improved curve fitting procedures to determine equilibrium binding constants
โ Scribed by Stootman, Frank H.; Fisher, Dianne M.; Rodger, Alison; Aldrich-Wright, Janice R.
- Book ID
- 119967669
- Publisher
- Royal Society of Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 347 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0003-2654
- DOI
- 10.1039/B604686J
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๐ SIMILAR VOLUMES
The binding of drugs to plasma proteins has been studied extensively using a variety of methods, including equilibrium dialysis. Published information on controls used in these studies is frequently inadequate; in other cases, there are deficiencies in the experimental design for the controls. A met
A multiparametric curve-fitting technique for pK, calculation has been adapted for use with a programmable calculator or microcomputer. This method provides for the convenient and accurate determination of the ionization constant in aqueous solution and of the apparent ionization constant in the pre