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Improved conditions for converting sterically hindered amides to 1,5-disubstituted tetrazoles

✍ Scribed by Gretchen M. Schroeder; Sydney Marshall; Honghe Wan; Ashok V. Purandare

Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
480 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis

Improved conditions for converting amides into 1,5-disubstituted tetrazoles are described. The optimum reaction conditions [diisopropyl azodicarboxylate (DIAD), diphenylphosphoryl azide (DPPA), and diphenyl-2-pyridyl phosphine in THF at 45 °C] converted sterically hindered amides to their corresponding tetrazoles in good yield.

📜 SIMILAR VOLUMES

ChemInform Abstract: Improved Conditions
ChemInform Abstract: Improved Conditions for Converting Sterically Hindered Amides to 1,5-Disubstituted Tetrazoles.
✍ Gretchen M. Schroeder; Sydney Marshall; Honghe Wan; Ashok V. Purandare 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB

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