✦ LIBER ✦

Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential

✍ Scribed by M. K. Johnson

Book ID: 104708749
Publisher: Springer-Verlag
Year: 1977
Tongue: English
Weight: 185 KB
Volume: 37
Category: Article
ISSN: 0340-5761
DOI: 10.1007/bf00293860

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✦ Synopsis

The assay of neurotoxic esterase (NTE) in brains taken from dosed hens enables potential neurotoxicity of organophosphate pesticides, plasticers, etc. to be assessed. The original assay [Johnson, M.K. Biochem. J. 114, 711-717 (1969)] has been simplified to eliminate centrifugation and transfer steps and both the selectivity and the sensitivity have been increased. The procedures necessary to obtain stable reagent stocks are described.

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