Improved anticoagulation management after palmaz schatz coronary stent implantation by sealing the arterial puncture site with a vascular hemostasis device
✍ Scribed by Kiemeneij, Ferdinand ;Jan Laarman, Gert
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 496 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0098-6569
No coin nor oath required. For personal study only.
✦ Synopsis
Sealing the arterial puncture site with a vascular hemostasis device has the potential to maintain optimal anticoagulation after stent implantation. The level of heparinization during the first 3 days after successful stent implantation was retrospectively compared between 2 groups of medically treated patients with (group A; n = 18) and without (group B; n = 17) a Vasoseal@ after sheath removal. The number of APTTs sampled in group A and B was 233 and 168, respectively. Respective mean values of APTT (seconds) in group A and B were 180 2 79 and 172 * 91 at day 1 (p = NS), 132 f 43 and 125 f 61 at day 2 (p = NS) and 123 2 36 and 116 & 48 at day 3 (p = NS). More A P n s were suboptimal (< 80 secs) in group B (34/168; 20%) compared to group A (171233; 7%) Ip < 0.001). More patients in group B compared to group A had 1 or more (14117; 82% vs. 8/18; 44%; p = 0.04), 2 or more (10117; 59% versus 3/18; 17%; p = 0.02) and 3 or more (8/17; 47% vs. 2/18; 11%; p = 0.03) suboptimal APTTs.
Bleeding complications were seen in 4 patients without and in 3 patients wlth a VasoseaP. Thus application of a vascular hemostasis device results in a less variable anticoagulation after coronary stenting, but it does not abolish entry site-related bleeding complications.