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Book ID
126428785
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
742 KB
Volume
75
Category
Article
ISSN
0009-2347

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Synthesis of the Nonpeptide Renin Inhibi
Synthesis of the Nonpeptide Renin Inhibitor A-68064 and the ACE Inhibitor Methyl Enalaprilat from (5S)-2,3,5,6-Tetrahydro-5-alkyl-N-(tert-butyloxycarbonyl-4H-1,4-oxazine-2-ones
✍ William R. Baker; Stephen L. Condon 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 218 KB

## The nonpeptide renin inhibitor, A-68064, and the ACE inhibitor methyl enalaprilat were synthesizedfrom (5S) 235,6-tetrahydro-S-benryI(bury2)-N-(tert-buto~car~nyl)~H~l fl-oxazine-2-ones la and 76, and (5s) 2.3,S,6-tetrahydro-5methyl-N-(fert-butoxycarbonyl)-4H-l.4-oxazine-2-one 12, respectively.