Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300 MHz in vivo EPR measurement

Competition of nitroxyl contrast agents

Competition of nitroxyl contrast agents as an in vivo tissue redox probe: Comparison of pharmacokinetics by the bile flow monitoring (BFM) and blood circulating monitoring (BCM) methods using X-band EPR and simulation of decay profiles

✍ Aya Okajo; Ken-ichiro Matsumoto; James B. Mitchell; Murali C. Krishna; Kazutoyo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

## Abstract Nitroxyl radicals used as tissue redox‐sensitive contrast agents in electron paramagnetic resonance (EPR) and/or NMR imaging should satisfy the following two conditions: 1) the molecules disperse into tissues rapidly, and 2) paramagnetic loss occurs by simple reduction of the radical. T

Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300&#xa0;MHz in vivo EPR measurement

Importance of volume limitation for tissue redox status measurements using nitroxyl contrast agents: A comparison of X-band EPR bile flow monitoring (BFM) method and 300 MHz in vivo EPR measurement