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Importance of the O6 position of guanine residues in the binding of DNA methylase to DNA

โœ Scribed by Paul A. Hepburn; Michael J. Tisdale


Book ID
118007792
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
339 KB
Volume
1088
Category
Article
ISSN
0167-4781

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Although adducts resulting from the reaction of mitomycin C (MC) and DNA have been characterized as guanine derivatives covalently linked to MC at the guanine N2-and/or 06-positions, lack of material and of protons on the guanine nucleus had led to difficulties in product characterization. Authentic