✦ LIBER ✦

Importance of strain differences in evaluations of learning and memory processes in null mutants

✍ Scribed by Wehner, Jeanne M. ;Silva, Alcino

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 769 KB
Volume: 2
Category: Article
ISSN: 1080-4013
DOI: 10.1002/(sici)1098-2779(1996)2:4<243::aid-mrdd8>3.0.co;2-r

No coin nor oath required. For personal study only.

✦ Synopsis

Complex behaviors such as learning and memory are regulated by multigenic systems. The advent o f new animal models created by recombinant DNA technology has provided a set o f genetic tools whereby the role of specific candidate genes in acquisition and retention of new information can be examined. These techniques include the creation of null mutant mice. Because of the polygenic nature o f complex behaviors, the impact o f single gene manipulations will in part depend on the genetic background of the mouse. This review addresses the relationship of endogenous strain differences in complex learning performance using a number of learning and memory paradigms t o the analyses of null mutants. Limitations t o the current technology and possible future advances are discussed.

📜 SIMILAR VOLUMES

The importance of learning processes in

The importance of learning processes in wind power development

✍ Kamp, Linda M. 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

## Abstract This paper examines four learning processes that occur simultaneously during wind turbine development and diffusion: learning by searching, learning by doing, learning by using, and learning by interacting. It considers how these different learning processes affect technology developmen

Microcompartmentation of cAMP in wild-ty

Microcompartmentation of cAMP in wild-type and memory-mutant dunce strains of Drosophila melanogaster

✍ Peter Friedrich; Magda Solti; Henrik Gyurkovics 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB

The "enzyme-probe" method [Solti M, Friedrich P: Eur J Biochem 95:551, 1979] has been applied to characterize the cyclic AMP pool in wild-type Canton-S and memory-mutant dunceM11 strains of Drosophila melanogaster. The kinetics of cyclic AMP breakdown in whole fly homogenates by endogenous cyclic nu

Development of learning and memory in mi

Development of learning and memory in mice genetically selected for differences in brain weight

✍ Barbara H. Herman; Dr. Z. Michael Nagy 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 685 KB

Working memory in spatial knowledge acqu

Working memory in spatial knowledge acquisition: Differences in encoding processes and sense of direction

✍ Wen Wen; Toru Ishikawa; Takao Sato 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 703 KB

‘I Remember When I Learned That!’ develo

‘I Remember When I Learned That!’ developmental and gender differences in children's memories of learning episodes

✍ Rhyannon H. Bemis; Michelle D. Leichtman; David B. Pillemer 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 113 KB

## Abstract Eighty 4‐ to 9‐year‐old children answered factual knowledge questions in math, science and social studies during one‐on‐one interviews. Children indicated whether they had known or guessed each answer, and whether they (a) remembered the moment they learned the answer (episodic response

Components of recognition memory: Dissoc

Components of recognition memory: Dissociable cognitive processes or just differences in representational complexity?

✍ Rosemary A. Cowell; Timothy J. Bussey; Lisa M. Saksida 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 676 KB

## Abstract Many current theoretical views within the literature on recognition memory—a representative sample of which is provided by the present special issue—advocate the dissociation of recognition memory into two cognitive processes: familiarity‐based recognition, and recollection/recall. Furt