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Importance of Host Genetic Factors HLA and IL28B as Predictors of Response to Pegylated Interferon and Ribavirin

✍ Scribed by de Rueda, Paloma Muñoz; López-Nevot, Miguel-Ángel; Sáenz-López, Pablo; Casado, Jorge; Martín-Casares, Antonia; Palomares, Pablo; Quiles, Rosa; Gila, Ana; Romero-Gómez, Manuel; Pavón, Esther-José; Muñoz, José-Antonio; Carazo, Ángel; Sanz-Cameno, Paloma; Moreno-Otero, Ricardo; Diago, Moisés; León, Josefa; Ruiz-Extremera, Ángeles; Salmerón, Javier


Book ID
121013811
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
218 KB
Volume
106
Category
Article
ISSN
0002-9270

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Association of IL28B variants with respo
✍ Naoya Sakamoto; Mina Nakagawa; Yasuhito Tanaka; Yuko Sekine-Osajima; Mayumi Ueya 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB

## Abstract Genetic polymorphisms of the interleukin 28B (IL28B) locus are associated closely with outcomes of pegylated‐interferon (PEG‐IFN) plus ribavirin (RBV) combination therapy. The aim of this study was to investigate the relationship between IL28B polymorphism and responses to therapy in pa