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Importance of DNA fragmentation in apoptosis with regard to TUNEL specificity

โœ Scribed by A Negoescu; C Guillermet; P Lorimier; E Brambilla; F Labat-Moleur


Book ID
117576120
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
1015 KB
Volume
52
Category
Article
ISSN
0753-3322

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Detection of DNA fragments in situ using the terminal deoxyribonucleotidyl transferase (TDTbmediated dUTP-digoxigenin nick end labeling (TUNEL) assay is increasingly applied to investigate active cell death (apoptosis). We studied the specificity of the assay i n well-defined models of apoptosis and