## Abstract Epidemiological studies indicate that nonsteroidal anti‐inflammatory drugs (NSAIDs) are neuroprotective, although the mechanisms underlying their beneficial effect remain largely unknown. Given their well‐known adverse effects, which of the NSAIDs is the best for neurodegenerative disea
✦ LIBER ✦
Implications of prostaglandin E2 synthesis and phospholipase C activation in potentiation of T-cell proliferation by LF 1695
✍ Scribed by Philippe Derrepas; Jocelyne Annat; Patrick Dutartre; Marc Pascal
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 490 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
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In mouse C3H 10T1/2 cells, we previously reported that TGF-beta1 first delays and later potentiates EGF-induced DNA synthesis corresponding to an inhibition of EGF-induced cyclin D1 expression at t = 13 h. We report here that in accord with DNA synthesis kinetics, TGF-beta1 initially suppresses EGF-