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Implications of MYCN amplification in patients with stage 4 neuroblastoma who undergo intensive chemotherapy

✍ Scribed by Sachiyo Suita; Tatsuro Tajiri; Michio Kaneko; Misako Hirai; Hideo Mugishima; Toru Sugimoto; Yoshiaki Tsuchida

Book ID
116686238
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
319 KB
Volume
42
Category
Article
ISSN
0022-3468

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High-dose chemotherapy followed by locor
High-dose chemotherapy followed by locoregional irradiation improves the outcome of patients with international neuroblastoma staging system Stage II and III neuroblastoma with MYCN amplification
✍ Anne Laprie; Jean Michon; Olivier Hartmann; Caroline Munzer; Marc-David Leclair; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 106 KB

## Abstract ## BACKGROUND The objective of this study was to determine whether systemic and regional, intensified treatment can improve the outcome of children who present with a localized neuroblastoma (NB) with __MYCN__ amplification (MNA). ## METHODS Between 1990 and 2000, 610 children with l