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Implications of coagulation factor VIII and IX pharmacokinetics in the prophylactic treatment of haemophilia

✍ Scribed by P. W. COLLINS; K. FISCHER; M. MORFINI; V. S. BLANCHETTE; S. BJÖRKMAN; ON BEHALF OF INTERNATIONAL PROPHYLAXIS STUDY GROUP (IPSG) PHARMACOKINETICS EXPERT WORKING GROUP


Book ID
108775596
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
128 KB
Volume
17
Category
Article
ISSN
1351-8216

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Prophylactic dosing of factor VIII and f
✍ S. Björkman 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB

**Summary.** The high cost and limited availability of factor concentrates make dosing of factor VIII (FVIII) or factor IX (FIX) a crucial issue in the prophylactic treatment of haemophilia. It has often been recommended that this treatment should aim to maintain a minimum plasma level of 1% of norm