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Implication of telomerase activity and alternations of telomere length in the histologic characteristics of intracranial meningiomas

✍ Scribed by Han-Jung Chen; Cheng-Loong Liang; Kang Lu; Jui-Wei Lin; Chung-Lung Cho

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 171 KB
Volume: 89
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(20001115)89:10<2092::aid-cncr9>3.0.co;2-n

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✦ Synopsis

BACKGROUND.

Telomerase activity and telomere length have been shown to be involved in the control of cell proliferation and regulation of cell senescence. The expression of telomerase activity may endow cells with the capacity of unlimited proliferation and immortality. The authors examined the telomerase activity and telomere length of intracranial meningiomas to determine the relation between the results and the clinicopathologic behavior of these tumors.

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