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Implication of receptor activator of NF-κB ligand in Wnt/β-catenin pathway promoting osteoblast-like cell differentiation

✍ Scribed by Bin Nie 聂 斌, Shaoqiong Zhou 周韶琼…

Book ID
120886438
Publisher
Springer-Verlag
Year
2012
Tongue
Chinese
Weight
498 KB
Volume
32
Category
Article
ISSN
0510-9752

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The osteoprotegerin (OPG)/receptor activator of nuclear factor-κB ligand (RANKL)/receptor activator of NF-κB (RANK) system plays an important role in the pathogenesis of metabolic bone diseases. This study is aimed to investigate effects and mechanisms of RANKL gene silencing on the function of huma