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Implication of protein tyrosine phosphatase 1B in MCF-7 cell proliferation and resistance to 4-OH tamoxifen

โœ Scribed by Christophe Blanquart; Salah-Eddine Karouri; Tarik Issad


Book ID
116298974
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
754 KB
Volume
387
Category
Article
ISSN
0006-291X

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As in other fields of biomedical research, the use of gene-targeted mice by homologous recombination in embryonic stem cells has provided important findings on the function of several members of the protein tyrosine phosphatase (PTP) family. For instance, the phenotypic characterization of knockout