Implementation of an intensive risk-stratified treatment protocol for children and adolescents with acute lymphoblastic leukemia in Lebanon
β Scribed by Samar Muwakkit; Carol Al-Aridi; Ahmad Samra; Raya Saab; Rami A. Mahfouz; Chantal Farra; Sima Jeha; Miguel R. Abboud
- Book ID
- 111994789
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 851 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0361-8609
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## Abstract Some cases of conversion from acute lymphoblastic leukemia (ALL) to acute nonlymphoblastic leukemia (ANLL) at relapse have been reported recently. We report three cases initially diagnosed as having ALL and showing morphological, cytochemical, and immunophenotypic features of ANLL at re
Four hundred thirty-four children, with good-risk acute lymphocytic leukemia (ALL), were assigned randomly to receive intensive or less intensive maintenance therapy with 6-mercaptopurine and methotrexate, plus vincristine and prednisone pulses in such a way that patients on treatment 1 had their le
A total of 125 children, who were diagnosed as having high-risk acute lymphoblastic leukemia (ALL), were treated with two consecutive protocols designated as AL851 (1985( -1988( ) and ALHR88 (1988( -1990)). All patients received induction therapy consisting of vincristine (VCR), prednisolone (PSL),