𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma

✍ Scribed by Jeffery A. Williams; Larry E. Dillehay; Kevin Tabassi; Eric Sipos; Christian Fahlman; Henry Brem

Book ID
110228445
Publisher
Springer US
Year
1997
Tongue
English
Weight
65 KB
Volume
32
Category
Article
ISSN
0167-594X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Protracted exposure radiosensitization o
Protracted exposure radiosensitization of experimental human malignant glioma
✍ Jeffery A. Williams; Jerry R. Williams; Xuan Yuan; Larry E. Dillehay πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 219 KB

Clinical modulation of radiosensitivity via combined fractionated high dose rate and continuous ultra-low dose rate irradiation (ULDR) holds promise for the radiosensitization of human malignant gliomas. We measured both the in vitro and in vivo responses of a human malignant glioma cell line to com

Implantable polymers for tirapazamine tr
Implantable polymers for tirapazamine treatments of experimental intracranial malignant glioma
✍ Xuan Yuan; Kevin Tabassi; Jeffery A. Williams πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 240 KB πŸ‘ 1 views

Malignant gliomas remain refractory to intensive radiotherapy and cellular hypoxia enhances clinical radioresistance. Under hypoxic conditions, the benzotriazine di-N-oxide (3-amino-1,2,4-benzotriazine 1,4-dioxide) (tirapazamine) is reduced to yield a free-radical intermediate that results in DNA da

IUdR polymers for combined continuous lo
IUdR polymers for combined continuous low-dose rate and high-dose rate sensitization of experimental human malignant gliomas
✍ Xuan Yuan; Larry E. Dillehay; Jerry R. Williams; Jeffery A. Williams πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 255 KB

## Abstract Local polymeric delivery enhances IUdR radiosensitization of human malignant gliomas (MG). The combined low‐dose rate (LDR) (0.03 Gy/h) and fractionated high‐dose rate (HDR) treatments result in cures of experimental MGs. To enhance efficacy, we combined polymeric IUdR delivery, LDR, an