The identification of (y-glutamy1)polyamines in proteolytic digest of proteins from the cytosolic and particulate fractions of B 16-F I 0 and B 16-F I OLr6 cell lines, originating from a spontaneous tumor in C57BL/6 mice, indicates that polyamines are incorporated into melanoma cell proteins by tran
β¦ LIBER β¦
Impairment of the metastatic activity of melanoma cells by transglutaminase-catalyzed incorporation of polyamines into laminin and Matrigel
β Scribed by A. Lentini; B. Provenzano; M. Caraglia; A. Shevchenko; A. Abbruzzese; S. Beninati
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 138 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0939-4451
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## Abstract Tissue factor, the cellular initiator of blood coagulation, has been implicated as a determinant of metastatic potential in human melanoma cells. Here, we report that differential expression of tissue factor in murine melanoma cell lines of known metastatic behavior is mediated by APβ1β