Splenic function and IgM-memory B cells
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Antonio Di Sabatino; M. Manuela Rosado; Paolo Cazzola; Paolo Biancheri; Francesc
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Article
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2008
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John Wiley and Sons
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English
โ 308 KB
๐ 2 views
Background: Under experimental chronic inflammation, tumor necrosis factor (TNF)-โฃ plays a role in damaging spleen marginal zone. This latter has a crucial function in mounting B cell-dependent immune responses against infections by encapsulated bacteria. In Crohn's disease (CD), a chronic inflammat