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Impairment of liver regeneration during inhibition of mitochondrial protein synthesis by oxytetracycline

✍ Scribed by Coby Van den Bogert; Menno Lont; Mart Mojet; Albert M. Kroon

Book ID
115718162
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
585 KB
Volume
722
Category
Article
ISSN
0005-2728

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Cycloheximide (Cyh), administered at a dose of 5 mg/kg body wt blocks protein synthesis in normal rat liver (NRL) and regenerating rat liver (RRL). The rate of synthesis of 45S pre-rRNA in RRL, studied after RNA labelling in vivo is activated 2.8 times. Pre-r RNA synthesis in RRL is more sensitive t