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Impaired surface antigen presentation in tumors: implications for T cell-based immunotherapy

✍ Scribed by Francisco Ruiz-Cabello; Teresa Cabrera; Miguel-Angel Lopez-Nevot; Federico Garrido


Book ID
112265055
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
498 KB
Volume
12
Category
Article
ISSN
1044-579X

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## Abstract Despite intensive treatment, 70% of the ovarian cancer patients will develop recurrent disease, emphasizing the need for new approaches such as immunotherapy. A promising antigenic target for immunotherapy in ovarian cancer is the frequently overexpressed p53 protein. The aim of the stu