Impaired salivary gland function reveals autonomic dysfunction in amyotrophic lateral sclerosis
β Scribed by Ralf Giess; Edgar Werner; Marcus Beck; Christoph Reiners; Klaus Victor Toyka; Markus Naumann
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 183 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0340-5354
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The objective of this study was to examine the contribution of lower motor neuron (LMN) and upper motor neuron (UMN) dysfunction to weakness and impaired motor control in 27 patients with amyotrophic lateral sclerosis (ALS). Isometric strength was measured by dorsiflexor maximum voluntary contractio
## Abstract Some previous functional magnetic resonance imaging (fMRI) studies have revealed increased activation in amyotrophic lateral sclerosis (ALS) patients but longitudinal data on such activation changes are lacking. To assess the time course of changes in fMRI patterns and their potential c