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Impaired post-transcriptional expression of interleukin-2 receptor in pokeweed mitogen-activated T cells

✍ Scribed by Oscar de la Calle-Martín; José Alberola-Ila; Pablo Engel; Julia Inglés; Virginia Fabregat; Joan Josep Barceló; Francisco Lozano; Teresa Gallart


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
587 KB
Volume
22
Category
Article
ISSN
0014-2980

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A 1-month-old boy with familial erythrophagocytic lymphohistiocytosis (FEL) had a barely detectable natural killer (NK) activity of 0% to 7% (median, 0.5%) with an effector/target ratio of 20:1. The number of Leu'/+ and Leull+ cells was within normal range. In terms of interleukin-2 (IL-2) receptor