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Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type

✍ Scribed by Megumi Yamamoto-Sasaki; Hiroki Ozawa; Toshikazu Saito; Michael Rösler; Peter Riederer

Book ID: 114004793
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 198 KB
Volume: 824
Category: Article
ISSN: 0006-8993
DOI: 10.1016/s0006-8993(99)01220-2

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## Abstract Acute myeloid leukemia (AML) in adults has a 20% 5‐year disease‐free survival despite treatment with aggressive cytotoxic chemotherapy. Previous work from our laboratory demonstrated that the majority of patients with acute lymphoid and myeloid leukemia overexpress CREB in the bone marr