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Impaired metabolism of leukotrienes in inherited metabolic disorders

✍ Scribed by E. Mayatepek; G. F. Hoffmann

Publisher
Springer
Year
1994
Tongue
English
Weight
218 KB
Volume
17
Category
Article
ISSN
0141-8955

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The in vitro metabolism of leukotriene B4 is initiated by omega-hydroxylation. This reaction is followed by oxidation of the omega-hydroxyl group to a carboxyl group. In vivo extensive beta-oxidation occurs and the main excreted products after administration of leukotriene B4 are water and carbon di