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Impaired liver regeneration in Ldlr−/− mice is associated with an altered hepatic profile of cytokines, growth factors, and lipids

✍ Scribed by Pauta, Montse; Rotllan, Noemi; Vales, Frances; Fernandez-Hernando, Ana; Allen, Ryan M.; Ford, David A.; Marí, Montserrat; Jiménez, Wladimiro; Baldán, Ángel; Morales-Ruiz, Manuel; Fernández-Hernando, Carlos

Book ID: 120520422
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 764 KB
Volume: 59
Category: Article
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2013.05.026

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The liver responds to injury with regulated tissue regeneration. During early regeneration, the liver accumulates fat. Neither the mechanisms responsible for nor the functional significance of this transient steatosis have been determined. In this study, we examined patterns of gene expression assoc