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Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

✍ Scribed by Garbi, Natalio; Tan, Pamela; Diehl, Alexander D.; Chambers, Benedict J.; Ljunggren, Hans-Gustaf; Momburg, Frank; Hämmerling, Günter J.


Book ID
109829047
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
151 KB
Volume
1
Category
Article
ISSN
1529-2908

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## Abstract Fetal thymic organ cultures of N15‐transgenic RAG‐2^–/–^ H‐2^b^ mice on normal, β‐2 microglobulin (β2M)^–/–^ or transporter associated with antigen processing (TAP‐1)^–/–^ MHCI‐deficient backgrounds were used to examine differentiation of thymocytes bearing a TCR specific for a viral pe