Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice

Impairment of contractile response to ca

Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice

✍ Marie-Louise Soulié; Gérard Cros; Jean-Jacques Serrano; Jean-Pierre Bali 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 331 KB

This work explored the role of the cholinergic pathway, assessed at a post-synaptic level by the use of isolated smooth muscle cells, in the impairment of antral motility associated with diabetic gastroparesis. Contractile response to carbachol--but not to erythromycin, a motilin receptor agonist--w