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Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1

โœ Scribed by E. van Dyk; P.J. Pretorius


Book ID
116508651
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
463 KB
Volume
495
Category
Article
ISSN
0378-1119

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โœ Arndt Vogel; Inge E.T. van den Berg; Muhsen Al-Dhalimy; John Groopman; Ching-Nan ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 508 KB

The murine model of hereditary tyrosinemia type 1 (HT1) was used to analyze the relationship between chronic liver disease and programmed cell death in vivo. In healthy fumarylacetoacetate hydrolase deficient mice (Fah(-/-)), protected from liver injury by the drug 2-(2- nitro-4-trifluoromethylbenzo