## Abstract Prenatal morphine exposure induces neurobiological changes, including deficits in learning and memory, in juvenile rat offspring. However the effects of this exposure on hippocampal plasticity, which is critical for learning and memory processes, are not well understood. The present stu
✦ LIBER ✦
Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure
✍ Scribed by Tan, Ji-Wei; Duan, Ting-Ting; Zhou, Qi-Xin; Ding, Ze-Yang; Jing, Liang; Cao, Jun; Wang, Li-Ping; Mao, Rong-Rong; Xu, Lin
- Book ID
- 124164035
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 333 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1355-6215
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## Abstract The central nervous system (CNS) exhibits remarkable plasticity in early life and can be altered significantly by various prenatal influences. We previously showed that prenatal exposure to morphine altered kinetic properties of N‐methyl‐D‐aspartate (NMDA) receptor‐mediated synaptic cur