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Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein

✍ Scribed by Olivier Disson; Delphine Haouzi; Solange Desagher; Kim Loesch; Michael Hahne; Eric J. Kremer; Chantal Jacquet; Stanley M. Lemon; Urszula Hibner; Hervé Lerat

Book ID
119757523
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
671 KB
Volume
126
Category
Article
ISSN
0016-5085

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## Abstract Hepatitis C virus (HCV) infection is often persistent, but its mechanism and pathogenesis remain unclear. One mechanism through which HCV escapes systemic immunosurveillance might be via impaired dendritic cells (DCs), which are the most potent type of antigen‐presenting cells. We exami