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Impaired bone anabolic response to parathyroid hormone in Fgf2−/− and Fgf2+/− mice

✍ Scribed by M.M. Hurley; Y. Okada; L. Xiao; Y. Tanaka; M. Ito; N. Okimoto; T. Nakamura; C.J. Rosen; T. Doetschman; J.D. Coffin

Book ID: 116292241
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 280 KB
Volume: 341
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.01.044

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## Abstract Disruption of the fibroblast growth factor 2 (FGF‐2) gene results in reduced bone mass in mice and impairs expression of bone morphogenic protein‐2 (BMP‐2) an important mediator of osteoblast and osteoclast differentiation. Since the relationship between FGF‐2 and BMP‐2 in bone remodeli

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