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Impaired blood–brain barrier function in angiotensinogen-deficient mice

✍ Scribed by Kakinuma, Yoshihiko; Hama, Hiroshi; Sugiyama, Fumihiro; Yagami, Ken-ichi; Goto, Katsutoshi; Murakami, Kazuo; Fukamizu, Akiyoshi


Book ID
109644252
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
201 KB
Volume
4
Category
Article
ISSN
1078-8956

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Cell culture models have been extensively used for studies of bloodbrain barrier (BBB) function. However, most in vitro models fail to reproduce the peculiar physiological and morphological properties of in situ brain microvascular endothelial cells. A recently developed, tridimensional and dynamic