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Impaired blood–brain and blood–spinal cord barriers in mutant SOD1-linked ALS rat

✍ Scribed by Charles Nicaise; Dinko Mitrecic; Pieter Demetter; Robert De Decker; Michèle Authelet; Alain Boom; Roland Pochet


Book ID
113504558
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
996 KB
Volume
1301
Category
Article
ISSN
0006-8993

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## Abstract Aquaporin 4(AQP4) is a water channel protein strongly expressed in the central nervous system in perimicrovessel astrocyte foot processes, the glia limitans, and ependyma. Expression of AQP4 is highest at the blood‐brain barrier and blood‐spinal cord barrier, supporting its critical fun