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Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia

✍ Scribed by Hajime Takayasu; Nana Nakazawa; Sandra Montedonico; Kaoru Sugimoto; Hideaki Sato; Prem Puri


Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
296 KB
Volume
23
Category
Article
ISSN
0179-0358

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The purpose of this study was to identify differentially expressed genes in normal and nitrofen-induced hypoplastic lungs in fetal mice. Such genes may play a role in the regulation of lung development. CD-1 pregnant dams were gavaged with 25 mg of nitrofen on gestational day (Gd) 8 to induce pulmon