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Impact on survival and leukemic transformation of in vitro growth pattern of granulocyte-macrophage progenitors (CFU-GM) in MDS

✍ Scribed by M. Garcia; G.F. Sanz; F. Arriaga; F. Lopez; M.A. Sanz


Book ID
113240063
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
91 KB
Volume
18
Category
Article
ISSN
0145-2126

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Two preparations of human interferon (IFN)-alpha were assessed for their influence on granulocyte-macrophage progenitor cells (CFU-GM) in vitro. Both highly purified human IFN-alpha Ly and recombinant IFN-alpha 2a suppressed CFU-GM colony formation in a dose-dependent manner using low-density bone-m