Impact of γ-chain cytokines on T cell homeostasis in HIV-1 infection: therapeutic implications

Impact of changes in antigen level on CD

Impact of changes in antigen level on CD38/PD-1 co-expression on HIV-specific CD8 T cells in chronic, untreated HIV-1 infection

✍ Thomas Vollbrecht; Heike Brackmann; Nadja Henrich; Joerg Roeling; Ulrich Seybold 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 371 KB

## Abstract Excessive immune activation is a hallmark of chronic uncontrolled HIV infection. During the past years, growing evidence suggests that immune inhibitory signals also play an important role in progressive disease. However, the relationship between positive and negative immune signals on