## Abstract ## Introduction Classical Hodgkin's Lymphoma (cHL) has been frequently associated with Epstein–Barr virus (EBV), which can be found in a latent pattern in Reed‐Sternberg (RS) cells. However, the impact of the presence of EBV in RS cells and its prognosis are still controversial. We ana
Impact of the Epstein–Barr virus positivity on Hodgkin's lymphoma in a large cohort from a single institute in Korea
✍ Scribed by Young Wha Koh, Dok Hyun Yoon, Cheolwon Suh, Jooryung Huh
- Book ID
- 120775576
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 376 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0939-5555
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## BACKGROUND. The incidence of Hodgkin's disease (HD) in Korea and other Asian countries is much lower than in western countries and its association with the Epstein-Barr virus has not been well characterized. ## METHODS. We evaluated the clinical, morphologic, and immunohistochemical features o
## Abstract The Epstein‐Barr virus (EBV)‐encoded latent membrane proteins (LMP1 and LMP2) are consistently expressed by malignant Hodgkin Reed‐Sternberg (HRS) cells of EBV‐associated Hodgkin's disease (HD). The EBV LMP1 has been implicated in tumorogenesis. Cytotoxic T lymphocyte (CTL) responses to