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Impact of the COMT Val108/158 Met and DAT genotypes on prefrontal function in healthy subjects

✍ Scribed by Xavier Caldú; Pere Vendrell; David Bartrés-Faz; Inmaculada Clemente; Núria Bargalló; María Ángeles Jurado; Josep Maria Serra-Grabulosa; Carme Junqué


Book ID
111867680
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
466 KB
Volume
37
Category
Article
ISSN
1053-8119

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## Abstract Working memory has been described as a neurocognitive probe of prefrontal brain functioning. Genetic variability related with catechol‐__O__‐methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention as a possible modulator of working memory tasks in both s