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Impact of the 1998 World Health Organization/International Society of Urological Pathology classification system for urothelial neoplasms of the kidney

✍ Scribed by Genega, Elizabeth M; Kapali, Malathy; Torres-Quinones, Marta; Huang, William C; Knauss, Jill S; Wang, Li-Ping; Raghunath, Puthiyaveettil N; Kozlowski, Christopher; Malkowicz, Stanley Bruce; Tomaszewski, John E

Book ID: 109888113
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 274 KB
Volume: 18
Category: Article
ISSN: 0893-3952
DOI: 10.1038/modpathol.3800268

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I n 1973, Dr. F. K. Mostofi proposed a three-tiered system (World Health Organization [WHO] Grades 1, 2, and 3) to grade urothelial (transitional cell) carcinoma of the urinary bladder. 1 Grading was based on the degree of anaplasia of tumor cells, which was defined as increased cellularity, nuclear