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Impact of targeted vector design on ColE1 plasmid replication

✍ Scribed by Reingard Grabherr; Karl Bayer

Book ID: 114152488
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 48 KB
Volume: 20
Category: Article
ISSN: 0167-7799
DOI: 10.1016/s0167-7799(02)01950-9

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## Abstract In this study, we systematically compare two vector design strategies for recombinant monoclonal antibody (Mab) synthesis by Chinese hamster ovary (CHO) cells; a dual open reading frame (ORF) expression vector utilizing separate cytomegalovirus (CMV) promoters to drive heavy chain (HC)