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Impact of Social Confrontation on Rat CD4 T Cells Bearing Different CD45R Isoforms

✍ Scribed by Volker Stefanski; George F. Solomon; Arthur S. Kling; John Thomas; Susan Plaeger


Book ID
115591349
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
170 KB
Volume
10
Category
Article
ISSN
0889-1591

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Rat CD4+ T cells are divided phenotypically by the anti-CD45RC monoclonal antibody OX22 into subsets with contrasting functions. Stimulation of T cells in vitro is known to induce a change in isoform from CD45RC+ to CD45RC-. We have investigated the in vifro conditions which promote a switch in isof